Whilst lower-count MBL almost never progresses to CLL, substantial-depend MBL progresses to CLL necessitating therapy in a level of 1% to 2% every year. Large-rely MBL is distinguished from Rai 0 CLL based upon whether the B-mobile rely is above or under 5 × 109/L. Whilst persons with both high-count MBL and CLL Rai stage 0 are at increased risk o